Searchable abstracts of presentations at key conferences in endocrinology

ea0081p534 | Adrenal and Cardiovascular Endocrinology | ECE2022

Reevaluation of the 1-mg overnight low-dose dexamethasone suppression test in the diagnosis of Cushing’s syndrome

Chehaider Cyrine , Oueslati Ibtissem , Terzi Amani , Yazidi Meriem , Chihaoui Melika

Introduction: The 1-mg overnight low-dose dexamethasone suppression test is used as a screening tool when Cushing’s syndrome is suspected. However, the biological confirmation of this syndrome is based upon the measurement of 24-hour urinary free cortisol and low-dose dexamethasone suppression test (Liddle test). The aim of this study was to assess the performance of the 1-mg overnight low-dose dexamethasone suppression test in the diagnosis of Cushing’s syndrome.</p...

ea0081ep773 | Pituitary and Neuroendocrinology | ECE2022

Clinical and paraclinical features of pituitary metastases: Report of five cases

Chehaider Cyrine , Oueslati Ibtissem , Yazidi Meriem , Chihaoui Melika

Introduction: The sellar region is known as a low-risk brain metastasis area. The prevalence of pituitary metastasis represents 1% of all surgical tumors of the pituitary gland. In most cases, pituitary metastasis is identified in patients with a prior history of cancer. In a few cases, it can reveal the primary tumor. The aim of this study was to assess clinical and paraclinical features of pituitary metastasis. Methods: This was a retrospective and des...

ea0081ep811 | Pituitary and Neuroendocrinology | ECE2022

Non-functional pituitary adenomas: clinical and paraclinical aspects

Grassa Anis , Chehaider Cyrine , Khessairi Nadia , Yazidi Meriem , Oueslati Ibtissem , Chihaoui Melika

Introduction: Non-functional pituitary adenomas (NFPAs) represent 30% of all pituitary adenomas and not associated with clinical evidence of hormonal hypersecretion. The aim of our study was to describe the clinical and paraclinical aspects of NFPAs.Methods: This is a retrospective descriptive study concerning 40 patients who were hospitalized in the endocrinology department of Rabta hospital in Tunis between January 2014 and December 2020. Clinical and ...

ea0081ep916 | Reproductive and Developmental Endocrinology | ECE2022

Swyer syndrome presenting with clinical features of cushing disease: a case report

Terzi Ameni , Yazidi Meriem , Chehaider Cyrine , Oueslati Ibtissem , Chaker Fatma , Chihaoui Melika

Introduction: Swyer syndrome is a rare sex development disorder characterized by pure 46 XY gonadal dysgenesis. It is associated with aberrations in testicular determination and differentiation leading to a female morphotype with presence of external and internal female genitalia, undifferentiated fibrous gonads, a male karyotype and hypergonadotropic hypogonadism. We present the case of a 46 XY adolescent female with complete gonadal dysgenesis diagnosed following her hospita...

ea0090ep111 | Adrenal and Cardiovascular Endocrinology | ECE2023

Coexistence of adrenocorticotropic hormone-dependent Cushing’s syndrome and papillary thyroid carcinoma

Sliman Chayma Bel Hadj , Najla Bchir , Chehaider Cyrine , Benchhida Annam , Chadia Zouaoui , Ouertani Haroun

Introduction: Papillary thyroid carcinoma is one of the most prevalent endocrine tumors. Adrenocorticotropic hormone (ACTH) dependent Cushing’s syndrome is a rare disease. We report a rare case of coexistence of papillary thyroid carcinoma and ACTH-dependent Cushing’s syndrome.Observation: A 59-year-old man, was admitted to our endocrinology department for exploration of bilateral adrenal incidentalomas discovered in an abdominal CT scan done i...

ea0090ep541 | Diabetes, Obesity, Metabolism and Nutrition | ECE2023

Insulin intolerance: Adipose panniculitis

Lachiheb Nabil , Mouna Elleuch , Cyrine Chehaider , Nadia Charfi , Kacem Faten Hadj , Mohamed Abid

Introduction: Besides insulin allergy, several other forms of insulin intolerance are possible. Adipose panniculitis (AP) is an acute form.Purpose: Describe the clinical, paraclinical and evolution of AP.Clinical case: 64-year-old patient, type 2 diabetic for 24 years on premixed human insulin for 10 years. He consults for itchy erythematous lesions at the insulin injection sites. The lesion begins with an immediate pruritus then a...

ea0099ep974 | Adrenal and Cardiovascular Endocrinology | ECE2024

The 1-mg overnight low-dose dexamethasone suppression test cut-off in establishing the diagnosis of Cushing’s syndrome

Terzi Amani , Oueslati Ibtissem , Merhbene Yasmine , Kamoun Elyes , Chehaider Cyrine , Yazidi Meriem , Chihaoui Melika

Introduction: The 1-mg overnight low-dose dexamethasone suppression test (DST) has been used to screen for mild autonomous cortisol secretion and Cushing’s syndrome (CS). The aim of the present study was to determine the DST discriminatory threshold confirming the diagnosis of CS.Methods: This was a monocentric retrospective study including patients who were admitted to the Department of Endocrinology of La Rabta Hospital, Tunis between 2014 and 202...

ea0099ep93 | Pituitary and Neuroendocrinology | ECE2024

Clinical and paraclinical characteristics of women with sheehan’s syndrome

Salhi Salma , Oueslati Ibtissem , Chehaider Cyrine , Grassa Anis , Terzi Amani , Chaker Fatma , Yazidi Meriem , Chihaoui Melika

Introduction: Sheehan’s syndrome is a rare cause of hypopituitarism. It is defined by an ischemic necrosis of the pituitary gland following postpartum hemorrhage. Sheehan syndrome is characterized by various endocrine deficiencies. The aim of the present study was to determine the clinical and paraclinical characteristics of women with Sheehan syndrome.Methods: This was a monocentric cross-sectional study including 50 women followed for Sheehan&#146...

ea0099ep470 | Pituitary and Neuroendocrinology | ECE2024

Infundibuloneurohypophysitis in sjögren’s syndrome: a case report

Terzi Ameni , Manel Jemel , Cyrine Chehaider , Meriem Adel , Marwa Chiboub , Hajer Kandara , Ines Kammoun

Introduction: Infundibuloneurohypophysitis (INH) is an autoimmune disease that typically presents as central diabetes insipidus (CDI). It is often more common in women with an autoimmune background. Here, we have the opportunity to describe an unusual case of a female patient who developed Sjögren’ syndrome (SJS) following CDI.Case presentation: A 55-year-old female was admitted to our department for exploration of polyuoropolydipsic syndrome e...

ea0081ep390 | Diabetes, Obesity, Metabolism and Nutrition | ECE2022

Uricemia in hypertensive type 2 diabetics: the forgotten metabolic parameter

Haj Kacem Akid Faten , Frikha Hamdi , Chehaider Cyrine , Salah Ameni , Ben Salah Dhoha , Mnif Mouna , Charfi Nadia , Mnif Fatma , Rekik Majdoub Nabila , Elleuch Mouna , Abid Mohamed

Introduction: Hyperuricemia is a common metabolic feature in patients with metabolic syndrome.Aim: The aim of our work is to study the correlation between uric acid level and the metabolic profile in hypertensive type 2 diabetic patients.Methods: This is a retrospective descriptive study of hypertensive type 2 diabetic patients followed in the endocrinology department of Hedi Chaker University Hospital of Sfax, Tunisia between 2019...